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KMID : 0191120090240030511
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Journal of Korean Medical Science
2009 Volume.24 No. 3 p.511 ~ p.512
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Clarithromycin Susceptibility Testing of Mycobacterium avium Complex Using 2,3-Diphenyl-5-thienyl-(2)-tetrazolium Chloride Microplate Assay with Middlebrook 7H9 Broth
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Park Young-Kil
Lee Sun-Min
Chang Chul-Hun L.
Kim Shin-Ok
Koh Won-Jung
Shin So-Nya
Kim Beom-Joon
Cho Sang-Nae
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Abstract
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A series of 119 Mycobacterium avium complex isolates were subjected to clarithromycin susceptibility testing using microplates containing 2,3-diphenyl-5-thienyl-(2)-tetrazolium chloride (STC). Among 119 isolates, 114 (95.8%) were susceptible to clarithromycin and 5 were resistant according to the new and the standard method. STC counts the low cost and reduces the number of procedures needed for susceptibility testing.
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KEYWORD
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Tetrazolium, Microtiter Method, Mycobacterium Avium Complex, Clarithromycin, Susceptibility Testing
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